| Autor: |
Patrícia Brasil, Christa Einspieler, Dajie Zhang, Peter B Marschik, Tara Kerin, Viviana Fajardo Martinez, Sophia Paiola, Thalia Mok, Mary C Cambou, Rashmi Rao, Fatima Ferreira, Trevon Fuller, Debika Bhattacharya, Suan-Sin Foo, Weiqiang Chen, Jae Jung, Karin Nielsen-Saines |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMJ Open, Vol 13, Iss 1 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2022-069194 |
| Popis: |
Objective To evaluate neuromotor repertoires and developmental milestones in infants exposed to antenatal COVID-19.Design Longitudinal cohort study.Setting Hospital-based study in Los Angeles, USA and Rio de Janeiro, Brazil between March 2020 and December 2021.Participants Infants born to mothers with COVID-19 during pregnancy and prepandemic control infants from the Graz University Database.Interventions General movement assessment (GMA) videos between 3 and 5 months post-term age were collected and clinical assessments/developmental milestones evaluated at 6–8 months of age. Cases were matched by gestational age, gender and post-term age to prepandemic neurotypical unexposed controls from the database.Main outcome measures Motor Optimality Scores Revised (MOS-R) at 3–5 months. Presence of developmental delay (DD) at 6–8 months.Results 239 infants were enrolled; 124 cases (83 in the USA/41 in Brazil) and 115 controls. GMA was assessed in 115 cases and 115 controls; 25% were preterm. Median MOS-R in cases was 23 (IQR 21–24, range 9–28) vs 25 (IQR 24–26, range 20–28) in controls, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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