Study of the Association of Vitamin D Receptor (VDR) Gene Polymorphism in Iraqi Patients with Inflammatory Bowel Disease

Autor: Abbas F. Abbas, Shiva Khezri, Ilham A. Khalaf, Alaa A. Al-Asadi, Safaa A. Abdulrazzaq
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Iraqi Journal of Industrial Research, Vol 10, Iss 1 (2023)
Druh dokumentu: article
ISSN: 2788-712X
DOI: 10.53523/ijoirVol10I1ID344
Popis: Inflammatory bowel disease (IBD) is a chronic inflammatory disorder divided into two types, Ulcerative colitis (UC), and Crohnʹs disease (CD). In total, 80 blood samples were collected for this study, 40 blood samples were collected from IBD and 40 blood samples were collected from healthy individuals as. Genomic DNA extracted from whole blood and (FokI) polymorphism was detected by polymerase chain reaction Restriction fragment length polymorphism (PCR- RFLP). The results of the statistical analysis showed high frequency and percentage in age group (< 30 years) was 16 (40%) with significant (P≤0.05) when compeered with control group. The frequency and percentage of body mass index (BMI) for the patient group was (27.91 ± 0.45). While BMI was (27.31 ± 0.54) for the control group with highly significant association (p
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