The clinical burden of cow's milk allergy in early childhood: A retrospective cohort study

Autor:	Katy Sorensen, Rosan Meyer, Kate E. Grimshaw, Abbie L. Cawood, Dionisio Acosta‐Mena, Rebecca J. Stratton
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	cow's milk allergy functional gastrointestinal disorders infants infections pediatrics primary care Immunologic diseases. Allergy RC581-607
Zdroj:	Immunity, Inflammation and Disease, Vol 10, Iss 3, Pp n/a-n/a (2022)
Druh dokumentu:	article
ISSN:	2050-4527
DOI:	10.1002/iid3.572
Popis:	Abstract Introduction Cow's milk allergy (CMA) is common in infants and children. Clinical presentations may vary, with a range of symptoms affecting the gastrointestinal (GI), skin and respiratory systems. Whilst the primary focus of research to date has been on the management of these symptoms, studies investigating the broader clinical burden of CMA are limited. Methods We performed a retrospective matched cohort study examining clinical data, including allergic symptoms and infections, extracted from case records within The Health Improvement Network database. A total of 6998 children (54% male) were included in the study, including 3499 with CMA (mean age at diagnosis 4.04 months) and 3499 matched controls without CMA, observed for a mean period of 4.2 years. Results GI, skin and respiratory symptoms affected significantly more children with CMA (p
Databáze:	Directory of Open Access Journals
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