Severe Quantitative Scale of Acanthosis Nigricans in Neck is Associated with Abdominal Obesity, HOMA-IR, and Hyperlipidemia in Obese Children from Mexico City: A Cross-Sectional Study

Autor: Ana I. Burguete-García, Alan Gilberto Ramírez Valverde, Meztli Espinoza-León, Isaac Sánchez Vázquez, Evelyn Yazmín Estrada Ramírez, Itzel Maldonado-López, Alfredo Lagunas Martínez, Cinthya Estefhany Diaz Benítez, Roberto Karam Araujo, Diana Fernández-Madinaveitia, Adriana E. Anides Fonseca, Miguel Cruz, José de Jesús Peralta Romero
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Dermatology Research and Practice, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 1687-6113
DOI: 10.1155/2022/2906189
Popis: Background. Acanthosis nigricans (AN) is a clinical sign that commonly occurs in obesity; however, its specificity and sensitivity have been controversial. It is unknown if AN severity degree can be a useful marker for cardiometabolic disorders screening. We suggest that the stratified analysis of AN severity degree in neck by Burke’s scale could be a useful tool in the screening of cardiometabolic alterations in obese children. Objective. The aim of this study was the association of AN severity degree in neck by Burke’s scale with anthropometric, biochemical, and inflammatory parameters in obese school-age children from Mexico City. Methods. A cross-sectional study was conducted, including 95 obese school-age children stratified by AN severity degree in neck by Burke’s scale. Anthropometric and fasting biochemical measurements were determined. Variables were compared by x2 test for frequencies and one-way ANOVA with Bonferroni posttest for continuous variables. Linear regression analysis adjusted by gender, BMI, and age was performed to evaluate the association between AN severity degree and cardiometabolic alterations. Statistical significance was set at p
Databáze: Directory of Open Access Journals
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