Perindopril metabolic effects and organo-protective action in metabolic syndrome patients

Autor:	V. B. Mychka, V. P. Masenko, N. V. Flegontova, D. M. Ataullakhanova, V. B. Sergienko, I. E. Chazova
Jazyk:	ruština
Rok vydání:	2007
Předmět:	arterial hypertension metabolic syndrome perindopril cerebral perfusion insulin resistance Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Кардиоваскулярная терапия и профилактика, Vol 6, Iss 2, Pp 34-41 (2007)
Druh dokumentu:	article
ISSN:	1728-8800 2619-0125
Popis:	Aim. To assess perindopril antihypertensive effects and its influence on metabolic disturbances, myocardial structure, and cerebral perfusion (CP) in patients with mild to moderate arterial hypertension (AH) and metabolic syndrome (MS) (AH + MS). Material and methods. Thirty patients with mild to moderate AH + MS participated in the study. At baseline and 24 weeks later, 24-hour blood pressure monitoring (BPM), carbohydrate and lipid metabolism, insulin sensitivity, myocardial structure and function, as well as CP parameters were assessed. Results. Target BP levels were achieved in 70% of the patients receiving perindopril: 9 and 21 patients were administered 4 and 8 mg/d, respectively. Fasting and postprandial glucose levels decreased significantly (both p
Databáze:	Directory of Open Access Journals
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