Prognostic Role of Tumor Microenvironment in DLBCL and Relation to Patients’ Clinical Outcome: A Clinical and Immunohistochemical Study

Autor:	Doaa Shams-Deen Ghorab, Ahmed Mohamed Helaly, Hoda Saleh El Mahdi, Moawiah Khatatbeh, Afaf Taha Ibrahiem
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Cytology QH573-671
Zdroj:	Analytical Cellular Pathology, Vol 2022 (2022)
Druh dokumentu:	article
ISSN:	2210-7185
DOI:	10.1155/2022/9993496
Popis:	Diffuse large B cell lymphoma is the most common type of lymphoma in Egypt with an unfavorable prognosis. The tumor microenvironment is rich in immune response either T cells or macrophages. The current study is aimed at testing CD4, CD8, CD68, and MMP9 immunohistochemistry of DLBCL activities with the prognosis of the tumor. The results showed no positive relation between T cell and macrophage reaction to the tumor prognosis suggesting that this reaction is part of the tumor process and not a defense mechanism from the surrounding stroma.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/de7e00ff74e445a09550e152443e1c03 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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