Plasmidome-analysis of ESBL-producing escherichia coli using conventional typing and high-throughput sequencing.

Autor: Alma Brolund, Oscar Franzén, Ojar Melefors, Karin Tegmark-Wisell, Linus Sandegren
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 6, p e65793 (2013)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0065793
Popis: Infections caused by Extended spectrum β-lactamase (ESBL)-producing E. coli are an emerging global problem, threatening the effectiveness of the extensively used β-lactam antibiotics. ESBL dissemination is facilitated by plasmids, transposons, and other mobile elements. We have characterized the plasmid content of ESBL-producing E. coli from human urinary tract infections. Ten diverse isolates were selected; they had unrelated pulsed-field gel electrophoresis (PFGE) types (
Databáze: Directory of Open Access Journals