Hippocampal volume and CDR-SB can predict conversion to dementia in MCI patients
| Autor: | João Guilherme Fiorani Borgio, Leonardo Baldaçara, Walter dos Santos Moraes, Acioly L. T. Lacerda, Maria Beatriz Montaño, Andrea Parolin Jackowski, Sérgio Tufik, Luiz Roberto Ramos, Rodrigo Affonseca Bressan |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Arquivos de Neuro-Psiquiatria, Vol 70, Iss 11, Pp 839-842 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1678-4227 0004-282X |
| DOI: | 10.1590/S0004-282X2012001100003 |
| Popis: | OBJECTIVE: To evaluate the combination of two factors: clinical dementia rating sum of boxes scores (CDR-SB) and hippocampal volume (HV) as predictors of conversion from mild cognitive impairment (MCI) to dementia. METHODS: Twenty-eight individuals (9 normal and 19 with MCI) were classified according to their CDR sum of boxes scores into 3 groups. RESULTS: The hippocampal volume was significantly lower in the high-risk group and in those who developed dementia after two years. The rate of conversion was crescent among the three groups. CONCLUSION: We were proposed an additional measurement of the hippocampal volume which may be helpful in the prognosis. However, we noted that the CDR-SB is a method as efficient as neuroimaging to predict dementia with the advantage of being a procedure for low cost and easy implementation, more consistent with public policy. |
| Databáze: | Directory of Open Access Journals |
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