Cooling of male rat skeletal muscle during endurance‐like contraction attenuates contraction‐induced PGC‐1α mRNA expression

Autor: Daisuke Hoshino, Ryota Wada, Yutaro Mori, Reo Takeda, Yudai Nonaka, Ryotaro Kano, Ryo Takagi, Yutaka Kano
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Physiological Reports, Vol 11, Iss 21, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2051-817X
DOI: 10.14814/phy2.15867
Popis: Abstract This study aimed to determine effects of cooling on contraction‐induced peroxisome proliferator‐activated receptor γ coactivator‐1α (PGC‐1α) and vascular endothelial growth factor (VEGF) gene expression, phosphorylations of its related protein kinases, and metabolic responses. Male rats were separated into two groups; room temperature (RT) or ice‐treated (COLD) on the right tibialis anterior (TA). The TA was contracted isometrically using nerve electrical stimulation (1‐s stimulation × 30 contractions, with 1‐s intervals, for 10 sets with 1‐min intervals). The TA was treated before the contraction and during 1‐min intervals with an ice pack for the COLD group and a water pack at RT for the RT group. The muscle temperature of the COLD group decreased to 19.42 ± 0.44°C (p
Databáze: Directory of Open Access Journals
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