Hydrophilic nanoparticles that kill bacteria while sparing mammalian cells reveal the antibiotic role of nanostructures

Autor: Yunjiang Jiang, Wan Zheng, Keith Tran, Elizabeth Kamilar, Jitender Bariwal, Hairong Ma, Hongjun Liang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-27193-9
Popis: Developing antibacterial agents which don’t have cytotoxic effects against mammalian cells is of interest for biomedical applications. Here, the authors explore how attaching inert polymer brushes to different sized nanoparticles can result in toxicity to bacteria but not to mammalian cells in a size dependent manner.
Databáze: Directory of Open Access Journals