Extra-gastrointestinal stromal tumour of the lesser omentum presenting as a massive intra-abdominal swelling: A case report and literature review

Autor: John Adi Ashindoitiang, Victor Ikechukwu Canice Nwagbara, Theophilus Ipeh Ugbem, Nkami Joseph Enya, Ikechimka Ogbugbanduchi Aniebo, Joseph Christopher Ekong, Sidney Esotu Obinna, Maurice Efana Asuquo
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Rare Tumors, Vol 16 (2024)
Druh dokumentu: article
ISSN: 2036-3613
20363613
DOI: 10.1177/20363613241242572
Popis: Extra gastrointestinal stromal tumour(EGIST) is rare and is regarded as gastrointestinal stromal tumour(GIST) that originates outside of the gastrointestinal tract. They originate from other intraabdominal tissues such as the omentum, mesentery and peritoneum. The cell of origin is the interstitial cell of Cajal(ICC), a pacemaker cell that controls gastrointestinal peristalsis and the tumor is characterized by the expression of KIT(CD117) a transmembrane tyrosine kinase receptor. Here, a 49-year-old female who presented with a 6 month history of abdominal pain, progressive abdominal swelling and the presence of an upper abdominal mass. She had surgical resection and adjuvant imatinib for the intraabdominal mass diagnosed on histology and immunohistochemistry as EGIST of the lesser omentum. Serial CT 14 months after surgery revealed no evidence of recurrence or metastasis. Clinicians should consider EGIST in the differential diagnosis of abdominal masses.
Databáze: Directory of Open Access Journals
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