Nephrotoxicity of checkpoint inhibitors; a current challenge

Autor: Samaneh Zandifar, Mahshid Imankhan, Padideh Daneii, Ali Azarpey, Leila Alem
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Nephropharmacology, Vol 13, Iss 1, Pp e10641-e10641 (2024)
Druh dokumentu: article
ISSN: 2345-4202
DOI: 10.34172/npj.2023.10641
Popis: Immune checkpoint inhibitors work by blocking the "checkpoint" mechanism that tumors use to hide from the immune system, therefore also weakening the immune system. Consequently, checkpoint inhibitors can cause autoimmune reactions, resulting in adverse effects. Prompt identification and management of adverse effects are critical for patients under checkpoint inhibitor therapy due to the potential severity and unpredictability of these immune-related adverse events.
Databáze: Directory of Open Access Journals