An overview on single nucleotide polymorphism studies in mastitis research
| Autor: | V. N. Muhasin Asaf, Amod Kumar, Abdul Rahim, Renjith Sebastian, Vysakh Mohan, Prashant Dewangan, Manjit Panigrahi |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Veterinary World, Vol 7, Iss 6, Pp 416-421 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0972-8988 2231-0916 |
| DOI: | 10.14202/vetworld.2014.416-421 |
| Popis: | Mastitis is an inflammatory condition of the mammary gland caused by microorganisms as diverse as bacteria, viruses, mycoplasma, yeasts and algae. Mastitis is an economically devastating disease mainly affecting the crossbred cattle in India. Control strategies against mastitis includes antibiotic therapy, vaccination, improvements in dairy cattle husbandry, farm and feeding management etc. but has met with little success.. Mastitis tolerance/susceptibility is difficult to measure directly and hence milk somatic cell count (SCC) or milk somatic cell score (SCS) is used as an indicator trait for mastitis as both traits are highly positively correlated. Single nucleotide polymorphism (SNP) marker is a single base change in a DNA sequence at a given position. SNP markers are the most preferred genetic markers nowadays. Currently most researches worldwide have been targeting molecular high density SNP markers that are linked to mastitis tolerance in an attempt to incorporate to understand the genetics of host resistance to mastitis and this knowledge will be helpful in formulating breeding programmes in an attempt to control mastitis. This article reviews various SNPs which are reported to be significantly associated with mastitis tolerance/susceptibility. |
| Databáze: | Directory of Open Access Journals |
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