Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair
Autor: | Yao Xiao, Zaijin Tao, Yufeng Ju, Xiaolu Huang, Xinshu Zhang, Xiaonan Liu, Pavel A. Volotovski, Chao Huang, Hongqi Chen, Yaozhong Zhang, Shen Liu |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Nano-Micro Letters, Vol 16, Iss 1, Pp 1-22 (2024) |
Druh dokumentu: | article |
ISSN: | 2311-6706 2150-5551 |
DOI: | 10.1007/s40820-024-01392-7 |
Popis: | Highlights The anti-adhesion effect of polylactic acid (PLA) membrane with diamond-like carbon (DLC) depositing is 44.72%, enhanced by 23.11% compared to PLA. DLC deposited on PLA membranes has been shown to effectively reduce the levels of reactive oxygen species, leading to a decrease in the expression of pro-inflammatory cytokines within peritendinous adhesion tissue. DLC decelerates PLA biodegradation and lactic production, which reduces the number of CD68+CD206+ macrophages within peritendinous adhesion tissue. |
Databáze: | Directory of Open Access Journals |
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