Evaluation of Pre-Malignant and Malignant Lesions in Cervico Vaginal (Pap) Smears by Nuclear Morphometry

Autor: Divya Rani M.N, Aparna Narasimha, Harendra Kumar ML, Sheela SR
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 8, Iss 11, Pp FC16-FC19 (2014)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2014/10367.5221
Popis: Background: Cervical cancer is the second most common cancer occurring among women worldwide, with almost half a million new cases each year. Normal cells gradually transform to form cancer cells through several stages. So, the changes occurring during the transformational stages need to be assessed. Aim: Our aim was to study various nuclear parameters useful in evaluating pre-malignant and malignant cervico-vaginal pap smears. Materials and Methods: Bethesda System was used to categorize cervical pap smears into premalignant and malignant lesions. Nuclear parameters were calculated using J 1.44C morphometric software. Several nuclear size parameters were analysed. Results: The nuclear area, perimeter, diameter were found to be statistically significant (p
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