Influence of cyclodextrins on the photostability of selected drug molecules in solution and the solid-state

Autor: B. D. Glass, M. E. Brown, S. Daya, M. S. Worthington, P. Drummond, E. Antunes, M. Lebete, S. Anoopkumar-Dukie, D. Maharaj
Jazyk: angličtina
Rok vydání: 2001
Předmět:
Zdroj: International Journal of Photoenergy, Vol 3, Iss 4, Pp 205-211 (2001)
Druh dokumentu: article
ISSN: 1110-662X
1110662X
DOI: 10.1155/S1110662X01000277
Popis: The photostability of selected drug molecules, including furosemide, prochlorperazine, diclofenac, piroxicam, midazolam and nifedipine was studied, the kinetics of photodegradation, identification of the photodegradants investigated and mechanisms of photodegradation proposed. Selected cyclodextrins altered the photodegradation profiles of diclofenac, piroxicam, midazolam and nifedipine by either accelerating or retarding the rate of photodegradation and generating novel photodegradants.
Databáze: Directory of Open Access Journals
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