| Autor: |
Rogério Heggendorn Sayão Filho, Marcos Vinicius Perini, José Arnaldo Cruz, Juliana Requena, Hermes Vieira Barbeiro, Nilza Trindade Molan, Fabio Pinatel Lopasso, Luiz Augusto Carneiro D'Albuquerque, Ivan Cecconello |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Acta Cirúrgica Brasileira, Vol 28, Iss 9, Pp 646-651 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
0102-8650 |
| DOI: |
10.1590/S0102-86502013000900004 |
| Popis: |
PURPOSE: To investigate superoxide dismutase (SOD) activity in the portal vein endothelium and malondialdehyde acid (MDA) production in liver tissue of rats submitted to 70% hepatectomy. METHODS:Twelve rats were distributed in two groups (hepatectomy and sham). Animals were sacrificed on post operative day 1 and portal vein, liver tissue and blood samples were collected. Portal vein SOD production was measured using lucigenin-amplified chemiluminescence assays. MDA measurement was used as an index of oxidative stress through the formation of TBARS (Thiobarbituric Acid Reactive Species). RESULTS: There was no difference in post operative bilirrubin, AST, ALT levels between groups. DHL level was higher in the hepatectomy group (p=0.01). MDA production in the remnant liver tissue and endothelial portal vein SOD activity were also significantly (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
