| Autor: |
Sajjad Karim, Mona Al-Kharraz, Zeenat Mirza, Hend Noureldin, Heba Abusamara, Nofe Alganmi, Adnan Merdad, Saddig Jastaniah, Sudhir Kumar, Mahmood Rasool, Adel Abuzenadah, Mohammed Al-Qahtani |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Journal of King Saud University: Science, Vol 34, Iss 2, Pp 101760- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1018-3647 |
| DOI: |
10.1016/j.jksus.2021.101760 |
| Popis: |
Objective: Databases and softwares are important to manage modern high-throughput laboratories and store clinical and genomic information for quality assurance. Commercial softwares are expensive with proprietary code issue while academic versions have adaptation issue. Our aim was to develop an adaptable in-house software that can stores specimen and disease-associated genetic information in biobank to facilitate translational research. Methods: Prototype was designed as per the research requirements and computational tools were used to develop software under three tiers; Visual Basic and ASP.net for presentation tier, SQL server for data tier, and Ajax and JavaScript for business tier. We retrieved specimens from biobank using this software and performed microarray based transcriptomic analysis to detect differentialy expressed genes (DEGs) with FC ±2 and P-value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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