| Autor: |
Juan Chen, Zhen-Zhen Zhang, Yao-Kai Chen, Quan-Xin Long, Wen-Guang Tian, Hai-Jun Deng, Jie-Li Hu, Xian-Xiang Zhang, Pu-Liao, Jiang-Lin Xiang, Dao-Xin Wang, Peng Hu, Fa-Chun Zhou, Zhi-Jie Li, Hong-Mei Xu, Xue-Fei Cai, De-Qiang Wang, Yuan Hu, Ni Tang, Bei-Zhong Liu, Gui-Cheng Wu, Ai-Long Huang |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Genes and Diseases, Vol 7, Iss 4, Pp 535-541 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2352-3042 |
| DOI: |
10.1016/j.gendis.2020.03.008 |
| Popis: |
In December 2019, the corona virus disease 2019 (COVID-19) caused by novel coronavirus (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide. Few information on clinical features and immunological profile of COVID-19 in paediatrics. The clinical features and treatment outcomes of twelve paediatric patients confirmed as COVID-19 were analyzed. The immunological features of children patients was investigated and compared with twenty adult patients. The median age was 14.5-years (range from 0.64 to 17), and six of the patients were male. The average incubation period was 8 days. Clinically, cough (9/12, 75%) and fever (7/12, 58.3%) were the most common symptoms. Four patients (33.3%) had diarrhea during the disease. As to the immune profile, children had higher amount of total T cell, CD8+ T cell and B cell but lower CRP levels than adults (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
