Genetic characterisation and forensic importance of 20 Y-STRs in Han population from Anshan, Northeast of China

Autor: Yefang Diao, Atif Adnan, Qin Lin, Chang Sun, Lie Wang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Annals of Human Biology, Vol 47, Iss 5, Pp 478-482 (2020)
Druh dokumentu: article
ISSN: 0301-4460
1464-5033
03014460
DOI: 10.1080/03014460.2020.1781930
Popis: Background With a population of over 1.4 billion and 56 ethnic groups, China is the largest country in the world in terms of population. Han is the main ethnic group of China (93%). Aim To provide genetic data of Y chromosomal STRs from Anshan City, Northeast of China, for the first time, which will serve as a reference database for forensic and population studies. Subjects and methods We report data of 20 Y-chromosomal short tandem repeats (YSTRs) genotyped with the Goldeneye® 20Y kit in 270 Han individuals residing in Anshan City of China. Results A total of 170 alleles were observed on 20 Y-STRs. The gene diversities varied from 0.3460 (DYS391) to 0.9692 (DYS385). Overall haplotype diversity was almost 1 with 261 unique haplotypes, while the discrimination capacity (DC) was 0.9814. Pairwise Rst and Fst genetic analyses, MDS plot, N-J tree and PCA showed the genetic structure of Anshan Han population was significantly different from other minority groups like Tibetans and Kazakhs. Conclusions Results of this study showed that Goldeneye® 20Y system loci have strong discriminatory power in the Anshan Han population of China which makes this kit suitable for forensic applications in this ethnic group.
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