Inducible Clindamycin Resistance among Staphylococci Isolated from Burn Patients

Autor: KS Ghenghesh, E El-Turki, K Tawil, O Shawerf, A Zorgani
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Libyan Journal of Medicine, Vol 4, Iss 3, Pp 149-152 (2009)
Druh dokumentu: article
ISSN: 1819-6357
Popis: Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A total of 159 staphylococcal isolates from different clinical specimens from burn patients in Tripoli Burn Center were tested for inducible clindamycin resistance by the disk-diffusion induction test. Inducible clindamycin resistance was detected in 66.2% of 65 methicillin-resistant S. aureus isolates and in none of 55 methicillin-sensitiveS. aureus, 10 methicillin-resistant coagulase negative staphylococci and 29 methicllin-sensitive coagulase negative staphylococci isolates. In our setting, clindamycin can be used for the treatmentof infections due to staphylococci, but we recommend that staphylococci isolates, particularly methicillin-resistant S. aureus, are tested by the D-test before treatment.
Databáze: Directory of Open Access Journals