Chlorhexidine: An elixir for periodontics

Autor: Arthiie Thangavelu, Sahaya Stelin Kaspar, Ramesh Periannan Kathirvelu, Bhuvaneshwari Srinivasan, Soundarya Srinivasan, Rajasekar Sundram
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Pharmacy and Bioallied Sciences, Vol 12, Iss 5, Pp 57-59 (2020)
Druh dokumentu: article
ISSN: 0975-7406
DOI: 10.4103/jpbs.JPBS_162_20
Popis: Chlorhexidine is a cationic bisbiguanide with broad antibacterial activity, and wide spectrum of activity encompassing gram-positive and gram-negative bacteria, yeasts, dermatophytes and some lipophilic viruses. Its antibacterial action is due to the disruption of the bacterial cell membrane by the chlorhexidine molecules, increasing the permeability and resulting in cell lysis. Thus, chlorhexidine plays a key role in the dentistry and is used to treat or prevent periodontal disease, and has earned its eponym of the gold standard. This article reviews in detail about the mechanism of action, indications, forms and various studies related to chlorhexidine.
Databáze: Directory of Open Access Journals