Determination of L-Ascorbic Acid Using MBs-AOX/GO/IGZO/Al by Wireless Sensing System and Microfluidic Framework

Autor: Jung-Chuan Chou, You-Xiang Wu, Po-Yu Kuo, Chih-Hsien Lai, Yu-Hsun Nien, Si-Hong Lin, Siao-Jie Yan, Cian-Yi Wu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: IEEE Access, Vol 7, Pp 45872-45880 (2019)
Druh dokumentu: article
ISSN: 2169-3536
DOI: 10.1109/ACCESS.2019.2907964
Popis: In this paper, the L-ascorbic acid (L-AA) biosensor based on magnetic beads-ascorbate oxidase/graphene oxide/indium gallium zinc oxide/aluminum (MBs-AOX/GO/IGZO/Al) membrane was integrated with the potentiometric measurement system with the microfluidic framework in order to investigate the different sensing characteristics under the static condition and the dynamic condition. The L-AA biosensor showed the average sensitivity of 78.9 mV/decade (25 °C) under the static condition, and it showed the average sensitivity of 81.7 mV/decade (25 °C) at the optimal flow rate (25 μl/min). Besides, the XBee module was used to apply in the remote detection for the L-AA biosensor, and the experimental results were shown the average sensitivity of 78.7 mV/decade (25 °C). Moreover, we also investigated various experiments, such as temperature effect, hysteresis effect, and lifetime. These experimental results would be beneficial to the development of the L-AA biosensor based on electrochemical detection.
Databáze: Directory of Open Access Journals