Ex vivo study of molecular changes of stained teeth following hydrogen peroxide and peroxymonosulfate treatments

Autor: Paulo Wender P. Gomes, Simone Zuffa, Anelize Bauermeister, Andrés Mauricio Caraballo-Rodríguez, Haoqi Nina Zhao, Helena Mannochio-Russo, Cajetan Dogo-isonagie, Om Patel, Paloma Pimenta, Jennifer Gronlund, Stacey Lavender, Shira Pilch, Venda Maloney, Michael North, Pieter C. Dorrestein
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-023-43201-y
Popis: Abstract White teeth can give confidence and tend to be associated with a healthier lifestyle in modern society. Therefore, tooth-bleaching strategies have been developed, including the use of hydrogen peroxide. Recently, peroxymonosulfate has been introduced as an alternative bleaching method to hydrogen peroxide. Although both chemicals are oxidizing agents, their effects on the molecular composition of the stained teeth are yet unknown. In this study, the molecular profiles of teeth bleached with hydrogen peroxide and peroxymonosulfate were compared using Liquid Chromatography-Tandem Mass Spectrometry. Statistical analyses were used to assess the samples. In addition, reference spectral libraries and in silico tools were used to perform metabolite annotation. Overall, principal component analysis showed a strong separation between control and hydrogen peroxide and peroxymonosulfate samples (p
Databáze: Directory of Open Access Journals
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