Motion compensated whole-heart coronary cardiovascular magnetic resonance angiography using focused navigation (fNAV)

Autor: Christopher W. Roy, John Heerfordt, Davide Piccini, Giulia Rossi, Anna Giulia Pavon, Juerg Schwitter, Matthias Stuber
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-17 (2021)
Druh dokumentu: article
ISSN: 1532-429X
DOI: 10.1186/s12968-021-00717-4
Popis: Abstract Background Radial self-navigated (RSN) whole-heart coronary cardiovascular magnetic resonance angiography (CCMRA) is a free-breathing technique that estimates and corrects for respiratory motion. However, RSN has been limited to a 1D rigid correction which is often insufficient for patients with complex respiratory patterns. The goal of this work is therefore to improve the robustness and quality of 3D radial CCMRA by incorporating both 3D motion information and nonrigid intra-acquisition correction of the data into a framework called focused navigation (fNAV). Methods We applied fNAV to 500 data sets from a numerical simulation, 22 healthy subjects, and 549 cardiac patients. In each of these cohorts we compared fNAV to RSN and respiratory resolved extradimensional golden-angle radial sparse parallel (XD-GRASP) reconstructions of the same data. Reconstruction times for each method were recorded. Motion estimate accuracy was measured as the correlation between fNAV and ground truth for simulations, and fNAV and image registration for in vivo data. Percent vessel sharpness was measured in all simulated data sets and healthy subjects, and a subset of patients. Finally, subjective image quality analysis was performed by a blinded expert reviewer who chose the best image for each in vivo data set and scored on a Likert scale 0–4 in a subset of patients by two reviewers in consensus. Results The reconstruction time for fNAV images was significantly higher than RSN (6.1 ± 2.1 min vs 1.4 ± 0.3, min, p
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