Varicella outbreak trends in school settings during the voluntary single-dose vaccine era from 2006 to 2017 in Shanghai, China

Autor: Qiang-song Wu, Xian Wang, Jing-yi Liu, Yuan-fang Chen, Qi Zhou, Yan Wang, Ji-da Sha, Ze-liang Xuan, Lin-wei Zhang, Lu Yan, Yi Hu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 89, Iss , Pp 72-78 (2019)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2019.09.009
Popis: Objective: To investigate varicella outbreak trends among schoolchildren during the voluntary single-dose varicella vaccine (VarV) era in Shanghai, China. Methods: Trends in school varicella outbreaks from 2006 to 2017 were assessed using joinpoint regression models. The impacts of changes in single-dose VarV coverage among schoolchildren and implementation of post-exposure prophylaxis (PEP) strategies on outbreak trends were further analyzed. Results: In total, 265 varicella outbreaks involving 3263 cases were reported in Shanghai from 2006 to 2017. The number of outbreaks showed an increasing trend from 2006 to 2017 (t = 2.62, p = 0.026), especially in kindergartens. The proportion of breakthrough varicella cases among all outbreak-related cases showed an increasing trend from 30.4% in 2008 to 85.7% in 2017 (t = 7.45, p
Databáze: Directory of Open Access Journals