The clinical significance of low dose biotin supplements

Autor: Nicholas Angelopoulos, Rodis D. Paparodis, Ioannis Androulakis, Panagiotis Anagnostis, Anastasios Boniakos, Leonidas Duntas, Spyridon N. Karras, Sarantis Livadas
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Thyroid Research, Vol 16, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 1756-6614
DOI: 10.1186/s13044-023-00162-8
Popis: Abstract Background In the last decade, the combination of the widespread use of streptavidin–biotin technology and biotin–containing supplements (BCS) in the daily clinical practice, have led to numerous reports of erroneous hormone immunoassay results. However, there are no studies assessing the clinical and biochemical significance of that phenomenon, when treating patients with hypothyroidism. Therefore, a prospective study was designed to investigate the potential alterations in the measurement of thyroid hormone concentrations and clinical consequences in patients with hypothyroidism using low -dose BCS containing less than 300 μg/day. Methods Fifty-seven patients on thyroxine supplementation, as a result of hypothyroidism and concurrent use of BCS at a dose
Databáze: Directory of Open Access Journals
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