Rheological and Biological Properties of Adhesive Skin Secretions from Eupsophus vertebralis (Anura: Alsodidae)

Autor: Felipe A. Contreras, Daniela P. Sepúlveda, André Capaldo Amaral, José J. Nuñez, Eliane Trovatti, Elkin Y. Suárez-Villota
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientifica, Vol 2024 (2024)
Druh dokumentu: article
ISSN: 2090-908X
DOI: 10.1155/2024/2722351
Popis: Skin secretions from Patagonian ground frogs, Eupsophus vertebralis, have previously been reported as a potent proteinaceous adhesive with potential biomedical applications. Here, we conducted a rheological analysis indicating the mechanical robustness of these secretions, with a storage modulus ranging from 1 to 10 Pa. In addition, antimicrobial and cytotoxicity assays were performed, revealing no antimicrobial activity against both the Gram-positive and Gram-negative bacteria. The cytotoxicity results were intriguing, as three samples showed no harm, and one exhibited a severe cytotoxic effect on the human cell line MG63. These properties, as indicated by these preliminary results, reinforce their potential for practical applications in the industrial and medical sectors.
Databáze: Directory of Open Access Journals
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