Modulatory effect of pomegranate extract on TRPA1, TRPM2 and caspase-3 expressions in colorectal cancer induction of mice

Autor: Kaya İnan, Dağ Serpil, Mavioğlu Kaya Müge, Tanrıverdi Erdi Anil, Beşeren Hatice, Aşasın Gizem
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Türk Biyokimya Dergisi, Vol 47, Iss 5, Pp 612-619 (2022)
Druh dokumentu: article
ISSN: 1303-829X
DOI: 10.1515/tjb-2022-0099
Popis: This study aimed to evaluate the effects of pomegranate fruit extract (PFE) on levels of transient receptor potential (TRP) channel and caspase-3 (Casp-3) expressions, tumor necrosis factor-α (TNF-α), total sialic acid (TSA), reduced glutathione (GSH), and malondialdehyde (MDA) in mice with induced colorectal cancer (CRC) by investigating effects of PFE on in vitro mitotic index (MI).
Databáze: Directory of Open Access Journals