Predictors of post-extubation stridor in patients on mechanical ventilation: a prospective observational study

Autor: Aiko Tanaka, Akinori Uchiyama, Yu Horiguchi, Ryota Higeno, Ryota Sakaguchi, Yukiko Koyama, Hironori Ebishima, Takeshi Yoshida, Atsuhiro Matsumoto, Kanaki Sakai, Daisuke Hiramatsu, Naoya Iguchi, Noriyuki Ohta, Yuji Fujino
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-99501-8
Popis: Abstract The cuff leak test (CLT) has been widely accepted as a simple and noninvasive method for predicting post-extubation stridor (PES). However, its accuracy and clinical impact remain uncertain. We aimed to evaluate the reliability of CLT and to assess the impact of pre-extubation variables on the incidence of PES. A prospective observational study was performed on adult critically ill patients who required mechanical ventilation for more than 24 h. Patients were extubated after the successful spontaneous breathing trial, and CLT was conducted before extubation. Of the 191 patients studied, 26 (13.6%) were deemed positive through CLT. PES developed in 19 patients (9.9%) and resulted in a higher reintubation rate (8.1% vs. 52.6%, p
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