Time course of the triglyceride glucose index accumulation with the risk of cardiovascular disease and all-cause mortality

Autor:	Xue Tian, Shuohua Chen, Yijun Zhang, Xiaoli Zhang, Qin Xu, Penglian Wang, Shouling Wu, Anxin Wang, Yanxia Luo
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Cardiovascular disease All-cause mortality Triglyceride-glucose index Time course analysis Cohort study Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-12 (2022)
Druh dokumentu:	article
ISSN:	1475-2840
DOI:	10.1186/s12933-022-01617-2
Popis:	Abstract Background Future risk of cardiovascular disease (CVD) and mortality is associated with cumulative amount TyG index (cumTyG) exposure, while whether time course of TyG accumulation modulates the risk remains unclear. This study sought to examine the associations of cumTyG index accumulation time course with the risk of CVD and all-cause mortality. Methods We enrolled 51,734 participants free of CVD and underwent three examinations at year 2006, 2008, and 2010. CumTyG from baseline to the third examination was calculated. Time course of cumTyG accumulation was calculated as the slope of TyG versus time from 2006 to 2010, or as splinting the overall TyG index accumulation into early (cumTyG06 − 08) and late accumulation (cumTyG08 − 10). Participants were categorized by the combination of cumTyG
Databáze:	Directory of Open Access Journals
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