Comparison between typical primary and eunatraemic, eukalaemic hypoadrenocorticism: 92 cases

Autor: Adrien Joaquim Da Silva, Eilidh Gunn, Pedro Jose Guzmán Ramos, Robert Edward Shiel, Laura Bree, Carmel Therese Mooney
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Irish Veterinary Journal, Vol 77, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 2046-0481
DOI: 10.1186/s13620-024-00280-1
Popis: Abstract Background Naturally occurring hypoadrenocorticism is an uncommon endocrine disorder in dogs but has significant morbidity and mortality. Some dogs present with apparent glucocorticoid deficiency alone as evidenced by eunatraemia and eukalaemia. Few studies have compared dogs with hypoadrenocorticism with or without electrolyte disturbances and there are no large case series of affected dogs from Ireland. Methods Retrospective observational study. Results Ninety-two cases diagnosed with hypoadrenocorticism subdivided into those with supportive electrolyte disturbances (Group 1; n = 72) and those without (Group 2; n = 20). Dogs in Group 1 were significantly (p = 0.001) younger (4.0 (3.0–6.0) years) than dogs in Group 2 (6.0 (4.75–8.25) years). Dogs in Group 1 presented significantly more commonly with vomiting (Group 1: 52/71 (73.2%), Group 2: 6/20 (30.0%); p
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