Effect of group cognitive behavioral therapy on clinical outcome of patients with persistent high-risk HPV infection

Autor: LONG Xin, JIANG Chenggang, HAN Rong
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: 陆军军医大学学报, Vol 46, Iss 6, Pp 618-622 (2024)
Druh dokumentu: article
ISSN: 2097-0927
DOI: 10.16016/j.2097-0927.202307078
Popis: Objective To explore the effect of group cognitive behavioral therapy (CBT) on the clinical outcome of patients with persistent high-risk human papillomavirus (HR-HPV) infection, and to construct a systematic psychological intervention treatment program for persistent HR-HPV infection patients with emotional disorders. Methods A total of 96 patients with persistent HR-HPV infection complicated with emotional disorder admitted in our hospital from September 2021 to March 2022 were recruited, and then randomly divided into an intervention group (n=44) and a control group (n=45) after 5 of them were excluded due to personal reason. The control group received health education and follow-up monitoring, and the intervention group received group CBT intervention additionally. Their clinical outcomes and psychological scale scores were compared between the 2 groups. Results In a follow-up for 6 and 12 months, the regression rate of HR-HPV infection was higher, and the sustained infection rate and progression rate of HR-HPV in the intervention group than the control group (P < 0.05). The intervention group also obtained lower scores of Nine-Item Patient Health Questionnaire (PHQ-9) and generalized anxiety scale (GAD-7) immediately after the intervention, and 6 and 12 months in follow-up for when compared with the control group (P < 0.05). And the scores at above time points were statistically lower than those before intervention in the intervention group (P < 0.05), but no such differences were observed in the control group (P>0.05). Conclusion Systematic psychological intervention treatment is beneficial to HR-HPV infection subside for patients with persistent HR-HPV infection. [Key words] human papillomavirus , cognitive behavioral therapy , cervix, reversion ,
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