Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis

Autor: Caitlin R. Francis, Hayle Kincross, Erich J. Kushner
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-32853-5
Popis: The promiscuous GTPase Rab35 has been shown to be involved in many important cellular functions. In this article, Francis et al. illustrate how Rab35 acts as a critical brake to actin remodeling during sprouting angiogenesis and how it is necessary for proper blood vessel development.
Databáze: Directory of Open Access Journals