Association Between Serum Uric Acid Levels and Atrial Fibrillation Risk
| Autor: | Chun-Hong Zhang, Dang-Sheng Huang, Dong Shen, Li-Wei Zhang, Yong-Jiang Ma, Yu-Mei Wang, Hong-Yan Sun |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Cellular Physiology and Biochemistry, Vol 38, Iss 4, Pp 1589-1595 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1015-8987 1421-9778 |
| DOI: | 10.1159/000443099 |
| Popis: | Background: Several studies were published to assess the association between serum uric acid levels and atrial fibrillation risk, but no consistent results were reported. We performed a meta-analysis to evaluate the evidence of the association between hyperuricemia and atrial fibrillation risk. Material/Methods: Pubmed and Embase databases were searched for prospective cohort studies assessing the association between hyperuricemia and atrial fibrillation risk. Relative risks (RRs) with corresponding 95% confidence intervals (95%CIs) were pooled using random-effect of meta-analysis to assess the risk of atrial fibrillation in individuals with hyperuricemia. Results: Six cohort studies were finally included into the meta-analysis. Meta-analysis of those 6 studies showed that hyperuricemia was significantly associated with increased risk of atrial fibrillation (RR = 1.49, 95%CI 1.24-1.79, P Conclusions: Based on the currently available data, hyperuricemia is associated with increased risk of atrial fibrillation. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|