Does metabolic control of the disease related with bone turnover markers in children with type 1 diabetes mellitus in Turkey?

Autor:	Merve Sena Topkaya, Onur Akın, Tuğba Küçükkasap Cömert
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Type 1 diabetes mellitus Oxidative stress Bone biomarkers Metabolic control Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	1472-6823
DOI:	10.1186/s12902-024-01553-0
Popis:	Abstract Background The aim was to evaluate the effect of metabolic control on bone biomarkers in children with type I diabetes. Materials and methods The children were divided into two groups according to their glycated hemoglobin (HbA1c) (%) levels: a group with HbA1c levels 8% (n = 18). The serum total oxidative status (TOS) (µmol/L), total antioxidant status (TAS) (mmol/L), alkaline phosphatase (ALP) (IU/L), osteocalcin (OC) (ng/ml), procollagen type-1-N-terminal peptide (P1NP) (ng/ml), and vitamin D (IU) levels and food consumption frequencies were determined. Results When patients were classified according to HbA1c (%) levels, those with HbA1c levels 8% (p %8). Conclusion HbA1c and serum TOS levels had an effect on bone turnover biomarkers in individuals with type I diabetes.
Databáze:	Directory of Open Access Journals
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