Fermented black rice and blueberry with Lactobacillus plantarum MG4221 improve UVB-induced skin injury

Autor: Seo Hyun Park, Jae Gon Kim, Young Ah Jang, Al Borhan Bayazid, Beong Ou Lim
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Food and Agricultural Immunology, Vol 32, Iss 1, Pp 499-515 (2021)
Druh dokumentu: article
ISSN: 0954-0105
1465-3443
09540105
DOI: 10.1080/09540105.2021.1967300
Popis: Chronic ultraviolet (UV) exposure causes skin injury thorough the production of reactive oxygen species (ROS). Skin dryness, a characteristic of UV-induced injury, is closely related to skin barrier dysfunction. We investigated the effect of fermented black rice and blueberry with Lactobacillus plantarum (FBBBR) on UVB-induced skin injury. In vitro, FBBBR suppressed UVB-induced ROS generation, apoptosis, and metalloproteinase-9 expression, while increasing the expression of collagen type 1 alpha 1 (COL1A1) gene and natural moisturising factor-related genes such as filaggrin (FLG) and transglutaminase-1 (TGM-1). Oral administration of FBBBR increased serum catalase activity and decreased serum IgE levels, improved stratum corneum hydration and epidermal thickness and enhanced FLG, TGM-1, involucrin, and COL1A1 mRNA expression in dorsal skin in UVB-irradiated hairless mice. Therefore, we suggest that FBBBR can be used as a functional food with beneficial effects on skin hydration and skin barrier function.
Databáze: Directory of Open Access Journals
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