Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats
| Autor: | Alireza Raji-amirhasani, Siavash Joukar, Vida Naderi boldaji, Mohammad-Abbas Bejeshk |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Iranian Journal of Basic Medical Sciences, Vol 21, Iss 6, Pp 558-563 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2008-3866 2008-3874 |
| DOI: | 10.22038/ijbms.2018.24796.6165 |
| Popis: | Objective(s): Considering the lack of information, the effects of mild endurance exercise plus blood flow restriction (BFR) on electrocardiographic parameters, hypertrophy index, and expression of angiotensin II receptors type 1 (AT1R) and type 2 (AT2R) and apelin receptor (APJ) were assessed in hearts of old male rats.Materials and Methods: Animal were grouped as control (CTL), Sham (Sh), lower extremities blood flow restriction (BFR), exercise (Ex), Sham + exercise (Sh + Ex), and blood flow restriction + exercise (BFR + Ex).Results: Exercise plus BFR significantly decreased the corrected QT (QTc) interval (PConclusion: Mild endurance exercise plus BFR can alter the expression of angiotensin II and apelin receptors that leads to cardiac hypertrophy and improves the ventricular conductivity of aging rats. |
| Databáze: | Directory of Open Access Journals |
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