Impact of Chronic Obstructive Pulmonary Disease on Risk of Recurrence in Patients with Resected Non-small Cell Lung Cancer
| Autor: | Guangliang QIANG, Qiduo YU, Chaoyang LIANG, Zhiyi SONG, Bin SHI, Yongqing GUO, Deruo LIU |
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| Jazyk: | čínština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Chinese Journal of Lung Cancer, Vol 21, Iss 3, Pp 215-220 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1009-3419 1999-6187 |
| DOI: | 10.3779/j.issn.1009-3419.2018.03.21 |
| Popis: | Background and objective Lung cancer and chronic obstructive pulmonary disease (COPD) are both common diseases in respiratory system and the leading causes of deaths worldwide. The purpose of this study was to determine whether the severity of COPD affects long-term survival in non-small cell lung cancer (NSCLC) patients after surgical resection. Methods A retrospective research was performed on 421 consecutive patients who had undergone lobectomy for NSCLC. Classification of COPD severity was based on guidelines of the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Characteristics among the three subgroups were compared and recurrence-free survivals were analyzed. Results A total of 172 patients were diagnosed with COPD, 124 as mild (GOLD-1), 46 as moderate(GOLD-2), and 2 as severe (GOLD-3). The frequencies of recurrence were significantly higher in higher COPD grades group (P |
| Databáze: | Directory of Open Access Journals |
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