Oil Red O positive vacuolated blasts in a case of CD45 negative, CD19 negative B-lymphoblastic leukemia

Autor: Diana O. Treaba, MD, Allison Chen, Chad Ellermeier, MD, Bradley DeNardo, MD, Rachel Altura, MD
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Human Pathology: Case Reports, Vol 6, Iss C, Pp 1-7 (2016)
Druh dokumentu: article
ISSN: 2214-3300
DOI: 10.1016/j.ehpc.2015.12.005
Popis: B-lymphoblastic leukemia is a clonal hematopoietic disorder of precursors B-lymphoblasts being most frequently encountered in children. Expression of CD19, a pan B-cell marker is noted in the majority of the cases with lack of CD19 expression being extremely rarely reported in the medical literature. We report the very rare case of a B-lymphoblastic leukemia with a triple negative immunophenotype: CD19 negative, CD45 negative and CD10 negative with vacuolated lymphoblasts and an aleukemic presentation in a 20-year-old man.
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