Health-related quality of life in outpatients with substance use disorder: evolution over time and associated factors

Autor: Melexima Simirea, Cédric Baumann, Michael Bisch, Hélène Rousseau, Paolo Di Patrizio, Sarah Viennet, Stéphanie Bourion-Bédès
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Health and Quality of Life Outcomes, Vol 20, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1477-7525
DOI: 10.1186/s12955-022-01935-9
Popis: Abstract Background Health-related quality of life (HRQoL) is an important element of patient care and clinical research. The aim of this study was to describe HRQoL changes and identify associated factors during a 6-month follow-up of outpatients starting care for alcohol or opioid dependence. Methods HRQoL was measured at baseline and 3 and 6 months later using the SF-12. Data on the patients’ sociodemographics, clinical characteristics and levels of anxiety and depression were collected using the Hospital Anxiety and Depression Scale (HADS). Repeated-measures analyses were performed to assess factors associated with global HRQoL differences and the evolution of HRQoL indicated by both physical and mental scores (PCS and MCS, respectively). Results The mean PCS and MCS scores were initially low at 45.4 (SD = 8.6) and 36.0 (SD = 10.9), respectively. The improvement in HRQoL was rapid in the first 3-month period and then slowed and remained stable over the subsequent 3-month period. Being employed (p = 0.012), having no comorbidities (p = 0.014) and having no depression (p = 0.004) were associated with significant differences in the average PCS scores at the 3 time points. Patients who had lower overall HRQoL MCS scores on average were those for whom a medication was initiated (p = 0.009), as was the case for patients with anxiety (p
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