Spatially resolved phosphoproteomics reveals fibroblast growth factor receptor recycling-driven regulation of autophagy and survival

Autor: Joanne Watson, Harriet R. Ferguson, Rosie M. Brady, Jennifer Ferguson, Paul Fullwood, Hanyi Mo, Katherine H. Bexley, David Knight, Gareth Howell, Jean-Marc Schwartz, Michael P. Smith, Chiara Francavilla
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-34298-2
Popis: Recruitment of Receptor Tyrosine Kinase signalling partners during endocytosis, specifically during recycling to the plasma membrane, is crucial to signal propagation and regulation. Here, the authors reveal FGFR signalling partners proximal to recycling endosomes with a spatially resolved phosphoproteomics approach.
Databáze: Directory of Open Access Journals