Validation of the Russian-language version of Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire

Autor: L. D. Vorobyova, T. V. Dubinina, A. O. Sablina, A. B. Demina, E. V. Ilinykh, K. V. Sakharova, I. A. Andrianova, T. V. Korotaeva, L. V. Ivanova
Jazyk: ruština
Rok vydání: 2024
Předmět:
Zdroj: Современная ревматология, Vol 18, Iss 4, Pp 43-50 (2024)
Druh dokumentu: article
ISSN: 1996-7012
2310-158X
DOI: 10.14412/1996-7012-2024-4-43-50
Popis: Objective: validation of the Russian-language version of Ankylosing Spondylitis Quality of Life (ASQoL) specific questionnaire for patients with ankylosing spondylitis (AS). Materials and methods. Тhe study included 100 patients with a definite diagnosis of AS according to the modified New York criteria of 1984. Patients were mostly men (58.5%), average age – 38.6±10 years, disease duration – 10.3±7.0 years, median disease activity by ASDAS-CRP – 2.32 [1.45; 2.94]. At the initial visit and after 3 months, all patients underwent a standard rheumatological examination, with assessment of the tender joint count (TJC) and swollen joint count (SJC) out of 44 joints assessed, the number of inflamed entheses using MASES index, spinal mobility using BASMI index. Assessment of patient reported outcomes included an assessment of spinal pain, night spinal pain, spinal pain during the day using a numerical rating scale, patient’s global assessment of health, assessment of functional status using BASFI index and health related quality of life (HRQoL) using EQ-5D, SF-36 and ASQoL questionnaires. To determine reliability of ASQoL questionnaire, a test-retest analysis and determination of internal consistency by calculating the Cronbach's α coefficient were used. The reliability of the questionnaire was analyzed in 39 patients. To assess the validity of the ASQoL questionnaire, i.e. its ability to reliably measure its inherent characteristics, construct and criterion validity were determined. The sensitivity of the questionnaire was assessed after 3 months during therapy in 79 patients. Results and discussion. According to the test-retest analysis, there was no difference between the initial assessment and re-assessment after 3 days (p>0.05), the Cronbach α coefficient was 0.884, indicating high reliability. Construct validity analysis was carried out using factor analysis and the “known groups” method. 3 main factors were identified: pain, physical health, emotional health. The “known groups” method showed that in patients with high disease activity according to ASDAS-CRP and BASDAI, HRQoL was significantly worse than in patients with low disease activity (р
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