Acute encephalomyelitis in a 52-year-old male post messenger ribonucleic acid severe acute respiratory syndrome coronavirus 2 vaccination: a case report

Autor: Pamela Lamisi Alebna, Muhammad Ahmad Shahid, Timothy Brannan, Ting Shen, Valentin Marian
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-5 (2023)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/s13256-023-03831-2
Popis: Abstract Background Acute disseminated encephalomyelitis is a well-known, but rare, side effect of some vaccines, or symptom following a febrile illness. Case A 69-year-old, otherwise healthy Hispanic male presented with acute fever, confusion, and later progressive weakness after receiving the first dose of the mRNA-1273 (Moderna) severe acute respiratory syndrome coronavirus 2 vaccine. Considering the progressive deterioration of the patient, despite being on multiple immunosuppressive agents, a brain biopsy was obtained, which revealed nonspecific meningoencephalitis. Conclusion In this case, we highlight the need for a regulatory framework to assist clinicians and patients with coverage of treatment for acute disseminated encephalomyelitis. The use of intravenous immunoglobulin in conjunction with glucocorticoids seems to be an effective treatment option.
Databáze: Directory of Open Access Journals
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