Genome-wide detections for runs of homozygosity and selective signatures reveal novel candidate genes under domestication in chickens

Autor:	Xiaodong Tan, Lu Liu, Jie Dong, Minjie Huang, Jiawen Zhang, Qinghai Li, Huanhuan Wang, Lijuan Bai, Ming Cui, Zhenzhen Zhou, De Wu, Yun Xiang, Weifen Li, Deqian Wang
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Indigenous chickens Genomic inbreeding Runs of homozygosity Selective signature Transcriptome VSTM2A Biotechnology TP248.13-248.65 Genetics QH426-470
Zdroj:	BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Druh dokumentu:	article
ISSN:	1471-2164
DOI:	10.1186/s12864-024-10349-4
Popis:	Abstract Background Indigenous chickens were developed through a combination of natural and artificial selection; essentially, changes in genomes led to the formation of these modern breeds via admixture events. However, their confusing genetic backgrounds include a genomic footprint regulating complex traits, which is not conducive to modern animal breeding. Results To better evaluate the candidate regions under domestication in indigenous chickens, we considered both runs of homozygosity (ROHs) and selective signatures in 13 indigenous chickens. The genomes of Silkie feather chickens presented the highest heterozygosity, whereas the highest inbreeding status and ROH number were found in Luhua chickens. Short ROH (
Databáze:	Directory of Open Access Journals
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