The use of posaconazole delayed-release tablets in the successful treatment of suspected mucormycosis in a bottlenose dolphin (Tursiops truncatus) calf

Autor: Gonçalo N. Marques, Nuno U. Silva, Miriam O. Leal, Carla A. Flanagan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Medical Mycology Case Reports, Vol 32, Iss , Pp 77-80 (2021)
Druh dokumentu: article
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2021.04.003
Popis: Mucorales infections in cetaceans have a high mortality rate. This case report refers to a bottlenose dolphin calf with suspected mucormycosis treated with posaconazole. This antifungal agent was discontinued after 96 days of therapy, however, the infection relapsed. Posaconazole was then resumed for a total of 255 days, with no signs of disease reactivation. The retrospective analysis of posaconazole serum levels in this successful case showed concentrations varying between 5.18 and 11.63 mg/L.
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