Evaluation of non-invasive marker of esophageal varices in cirrhosis of liver

Autor: Pardeep Kumar, Kuldeep Singh, Arun Joshi, Priyanka Thakur, Subodh Kumar Mahto, Brijesh Kumar, Nitasha Pasricha, Biswa Ranjan Patra, Brinder M. S Lamba
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Family Medicine and Primary Care, Vol 9, Iss 2, Pp 992-996 (2020)
Druh dokumentu: article
ISSN: 2249-4863
DOI: 10.4103/jfmpc.jfmpc_854_19
Popis: Introduction: Esophageal varices develop as a consequence of portal hypertension (PHT) in patients with chronic liver disease. Hence, screening of all cirrhotic patients with upper gastrointestinal endoscopy to detect the presence of significant esophageal varices implies a number of unnecessary endoscopies and has its limitation where such facilities are not available, especially in the rural part of country. Method: Patients with either sex, aged between 18 and 60 years with diagnosis of cirrhosis were studied. Detailed history, physical examination along with relevant investigations were recorded and upper gastrointestinal endoscopy was done within 2–3 days of investigation. Esophageal varices were graded as I-IV, using the Paquet grading system and patients were classified dichotomously either as having large esophageal varices (LEV) group A (Grade III-IV) and no varices group B (grade I-II). Result: A total of 50 patients with cirrhosis of liver were recruited in the study. Among hematological markers, only low platelet count was significantly associated with the presence of LEV (P value
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