Treatment results in the differential surgery of intradural extramedullary schwannoma of 110 cases.

Autor: Shaohui Zong, Gaofeng Zeng, Chunxiang Xiong, Bo Wei
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 5, p e63867 (2013)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0063867
Popis: STUDY DESIGN: A retrospective study of intradural extramedullary schwannoma. OBJECTIVE: The purpose of this study was to compare treatment results in the differential surgery of intradural extramedullary schwannoma. BACKGROUND: A reference guide to the surgical procedures available to treat intradural extramedullary schwannoma has not yet been established. METHODS: The study retrospectively reviewed 110 patients: Group A: laminectomy+microscopic excision; Group B: hemilaminectomy+microscopic excision; Group C: laminectomy+microscopic excision+pedicle screw fixation. Researchers selected patients for this retrospective review by applying the following criteria: 1) back pain spread out from the tumor level, sensory and motor loss; 2) treatment by surgery; 3) clinical diagnosis made by physical examination, magnetic resonance imaging (MRI), and pathology; 4) a minimum clinical and radiologic follow-up of 12 months. The clinical outcomes were assessed by comparing the Visual Analogue Pain Scores (VAS) and the Japanese Orthopedic Association Scores (JOA score). The study also performed a cost-effectiveness analysis. RESULTS: Cervical vertebrae: The estimated blood loss in Group B was significantly less than in Group C (P
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