| Autor: |
Jun’ichi Kobayashi, Yuzuru Mikami, Masashi Tsuda, Kazusei Komatsu, Yuu Kasai, Hideyuki Shigemori |
| Jazyk: |
angličtina |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Marine Drugs, Vol 2, Iss 4, Pp 164-169 (2004) |
| Druh dokumentu: |
article |
| ISSN: |
1660-3397 |
| DOI: |
10.3390/md204164 |
| Popis: |
Abstract: Two new cytotoxic twelve-membered macrolides, sporiolides A (1) and B (2), were isolated from the cultured broth of a fungus Cladosporium sp., which was separated from an Okinawan marine brown alga Actinotrichia fragilis, and the structures were elucidated by spectroscopic data. Sporiolides A (1) and B (2) exhibited cytotoxicity against murine lymphoma L1210 cells. Spoliolide A (1) showed antifungal activity against Cryptococcus neoformans and Neurospora crassa. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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