Quinacetophenone: A simple precursor to privileged organic motifs

Autor: El-Sayed Ibrahim El-Desoky, Mohamed Ahmed Abozeid, Abdel-Rahman Hassan Abdel-Rahman
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3380-3405 (2019)
Druh dokumentu: article
ISSN: 1878-5352
DOI: 10.1016/j.arabjc.2015.09.010
Popis: This review presents the chemistry of quinacetophenone and its utility as an easily accessible building block for the synthesis of various advantageous organic compounds. This versatile precursor can be easily synthesized via different synthetic methodologies such as Friedel–Crafts acetylation, Fries rearrangement and Hoesch reaction. Based upon its inherent chemical reactivity, the title compound has been utilized to construct various organic molecules such as chalcones, chromones, flavonoids, coumarins, quinones and azoles including various naturally and biologically active compounds. Keywords: Hydroxyacetophenone, Chalcone, Chromone, Flavone, Chromanone, Coumarin
Databáze: Directory of Open Access Journals